J. Michael Bishop, MD
University of California, San Francisco, San Francisco, California
Internationally recognized for his original research involving the viral and genetic basis of cancer initiation and progression, Dr. Bishop was awarded the 1989 Nobel Prize in Physiology or Medicine, along with Dr. Harold. E. Varmus, for their co-discovery of proto-oncogenes. This class of genes possesses normal biological functions that have the ability to promote carcinogenesis upon acquisition of various genetic abnormalities.
This discovery that cancer could be caused by the malfunction of normal genes revolutionized the understanding of tumorigenesis and greatly expanded the scope of associated scientific areas such as cancer detection as well as drug discovery and development. In addition to this finding, Dr. Bishop was equally instrumental in defining the molecular mechanisms of retroviral transduction as well as discovering the function of the protein product of the src oncogene, the first biochemical mechanism implicated directly in tumorigenesis.
2011 Raymond and Beverly Sackler Award, Research!America2009 DiNA Lifetime Achievement Award2008 Elected Foreign Member, The Royal Society, London2003 National Medal of Science1998 Chancellor, University of California, San Francisco1989 Nobel Prize in Physiology or Medicine1987 Elected Fellow, American Association for the Advancement of Science1984 Alfred P. Sloan, Jr., Prize, General Motors Cancer Research Foundation1984 Gairdner Foundation International Award1984 Armand Hammer Cancer Prize1983 Passano Foundation Award1982 California Scientist of the Year, California Museum of Science and Industry1982 Albert Lasker Award for Basic Medical Research1981 Director, The George Williams Hooper Research Foundation, University of California, San Francisco1962 MD, Harvard University