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FINDING CURES TOGETHER<sup>SM</sup>

Scientists on Science

Cancer at the Nanoscale‚Äč

A talk by Joe W. Gray, PhD

Dr. Joe W. Gray is the chair of Biomedical Engineering; director, of the Center for Spatial System Biomedicine; and associate director for Translational Research, Knight Cancer Institute at the Oregon Health and Science University (OHSU) and he holds the Gordon Moore endowed chair. His laboratory explores multiscale omic and structural of analyses of the functional consequences of molecular, cellular, and tissue level changes induced by genomic aberrations in cancer; mathematical models that describe how cancer-associated molecular abnormalities influence individual responses to therapeutic inhibitors; novel therapeutic strategies to treat breast or pancreatic cancer subpopulations that do not respond well to current therapies; and molecular imaging for early detection of metastasis prone breast cancer. He is a co-inventor of key aspects of BrdUrd/DNA analysis, fluorescence in situ hybridization, comparative genomic hybridization, and paired end sequencing.

His work is described in more than 400 publications and more than 80 US patents. Selected awards include the Research Award, Radiation Research Society, 1985; E.O. Lawrence Award, U.S. Department of Energy, 1986; Fellow, American Association for the Advancement of Science, 1996; Curt Stern Award, American Society for Human Genetics, 2001; Doctor of Medicine, Honoris Causa, Tampere University, Finland, 2005; Brinker Award for Scientific Distinction: Basic Science, 2007; Fellow of the American Institute for Medical and Biological Engineering, 2009; Member, Institute of Medicine, National Academy of Sciences, 2011; Lawrence Livermore National Laboratory Entrepreneur's Hall of Fame, 2012; Simon M. Shubitz Award for work in genome science, University of Chicago, 2012; Honorary Doctorate of Engineering, Colorado School of Mines, 2012; Nieuwland Lecture Series, University of Notre Dame, 2013; Alfred G. Knudson Award Lecture in Cancer Genetics, NCI, 2014.

Listen to Dr. Gray's talk on "Cancer at the Nanoscale."